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Creatine Supplementation May Protect Against Exercise-Induced Muscle Injury |
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Written by ryan
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Tuesday, 08 December 2009 |
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| | Summary# | 47621 | Topic: | Creatine Supplementation May Protect Against Exercise-Induced Muscle Injury | Keywords: | EXERCISE, IRONMAN - Creatine | Reference: | “Effect of short-term creatine supplementation on markers of skeletal muscle damage after strenuous contractile activity,†Bassit RA, Pinheiro CH, et al, Eur J Appl Physiol, 2009 Dec 3; [Epub ahead of print]. (Address: Departamento de Fisiologia e BiofÃsica, Instituto de Ciências Biomédicas I, Universidade de São Paulo, Av. Lineu Prestes, 1524, Sala 105, Butantan, São Paulo, SP, 05508-900, Brazil. E-mail:
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). | Summary: | In a study involving 8 Ironman triathletes, supplementation with creatine monohydrate (20 g/d) plus maltodextrin (50 g), divided into 2 equal doses, for 5 days prior to the Ironman competition was found to decrease plasma activities of creatine kinase, lactate dehydrogenase, and aldolase, and prevented the rise in glutamic oxaloacetic acid transaminase and glutamic pyruvic acid transaminase plasma activities - as compared to subjects who received a placebo (50 g/d maltodextrin only) who experienced a rise in these levels after the competition. The study also consisted of a trial involving rats, in which administration of creatine (5 g/d/kg body weight) for 5 days was found to delay fatigue, preserve force, and prevent the rise in LDH and CK plasma activities and muscle vascular permeability in the gastrocnemius muscle. The authors conclude, “CrS presented a protective effect on muscle injury induced by strenuous contractile activities.â€
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Creatine Supplementation Improves Neuromuscular Function |
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Written by ryan
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Tuesday, 08 September 2009 |
| Reference: | “Effect of Short-Term Creatine Supplementation on Neuromuscular Function,” Bazzucchi I, Felici F, et al, Med Sci Sports Exerc, 2009 Sept 2; [Epub ahead of print]. (Address: Department of Human Movement and Sport Sciences, Università degli Studi di Roma "Foro Italico," Roma, Italy). | | Summary: | In a randomized, double-blind study involving 16 moderately trained men (25.2 years of age), supplementation with creatine (5 g Cr + 15 mg maltodextrin, 4 times/d) for a period of 5 days was found to improve neuromuscular function of the elbow flexor muscle during voluntary and electrically induced contractions, as compared to subjects who received placebo (20 g maltodextrin, 4 times/d). In subjects who received creatine, peak torque of maximal twitch was 33.4% higher and the time to reach the peak torque was 54.7% lower than in subjects who received the placebo. Moreover, torque-angular velocity curve was enhanced and mean fiber conduction velocity was 8.9% higher at all angular velocities after supplementation with creatine. The authors conclude, “The present study shows that oral Cr supplementation improves neuromuscular function of the elbow flexor muscle during both voluntary and electrically induced contractions.” |
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